Current PTCTC Protocols
Below is a listing of current protocols that the PTCTC is involved in.
Current Protocols
Protocol | ClinicalTrials.gov NCT Number | Status | More Information |
|---|---|---|---|
BMT CTN 1702: Clinical Transplant-Related Long-Term Outcomes of Alternative Donor Allogeneic Transplantation | NCT03904134 | Active | https://web.emmes.com/study/bmt2/protocol/1702_protocol/1702_protocol.html |
BMT CTN 1507: Haploidentical Bone Marrow Transplantation in Sickle Cell Patients | NCT03263559 | Active | https://web.emmes.com/study/bmt2/protocol/1507_protocol/1507_protocol.html |
BMT CTN 1503: Comparing Bone Marrow Transplantation in Standard Care in Adolescents with Severe Sickle Cell Disease | NCT02766465 | Closing Soon | https://web.emmes.com/study/bmt2/protocol/1503_protocol/1503_protocol.html |
Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children and Young Adults with B-ALL (EndRAD) | NCT03509961 | Recruiting | https://clinicaltrials.gov/ct2/show/NCT03509961 |
Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia (TransIT) | NCT02845596 | Recruiting | https://clinicaltrials.gov/ct2/show/NCT02845596 |
The Role of KIR-favorably Mismatched Haploidentical Transplantation and KIR Polymorphisms in Determining Outcomes of Children with ALL/AML/MDS Undergoing Allogeneic hematopoietic Cell Transplantation | NCT02646839 | Enrolling by Invitation | https://clinicaltrials.gov/ct2/show/NCT02646839 |
Randomized trial of low versus moderate exposure busulfan for infants with severe combined immunodeficiency (SCID) receiving TCRαβ+/CD19+ depleted transplantation: A Phase II study by the Primary Immune Deficiency Treatment Consortium (PIDTC) and Pediatric Blood and Marrow Transplant Consortium (PBMTC) | NCT03619551 | Recruiting | https://clinicaltrials.gov/ct2/show/NCT03619551 |
Phase 1/2 Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and
Young Adults with Relapsed/Refractory Acute Myeloid Leukemia | NCT03971799 | Recruiting | https://clinicaltrials.gov/ct2/show/NCT03971799 |
Multi-center phase II randomized controlled trial of naïve T cell depletion for prevention of chronic graft-
versus-host disease in children and young adults | NCT03779854 | Recruiting | https://clinicaltrials.gov/ct2/show/NCT03779854 |
Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation (ACES) | NCT03475212 | Recruiting | https://clinicaltrials.gov/ct2/show/NCT03475212 |